While the roots of regenerative medicine go back decades, only in recent years has the treatment started to become more common. This is in no small part because of the contribution to the field by the renowned Dr. Cameron Clokie of Toronto Canada. Dr. Clokie started his career as a clinical dentist with a focus on the academic aspects of dentistry.
According to Crunchbase, Cameron Clokie has many credentials and experience, including being named as the Head of Oral and Maxillofacial Surgery. This title was granted in addition to Professor of Oral and Maxillofacial Surgery at the University of Toronto. Dr. Clokie retired from academics in 2017, to focus on other ventures.
Regenerative medicine is the closest thing to set the clock back that is found currently. Using a protein, bone is able to be regrown as if the patient is a baby again. It stimulates the same process that spurred bone development in babies and fetuses, growing a brand new bone from “scratch” so to speak.
Dr. Clokie is credited with recently being able to regrow part of a jawbone for a man who had lost his to a tumor. “With this patient, we’ve actually regrown a jawbone that is identical [to the one] he lost.” Dr. Clokie noted.
The protein that causes the regrowth is added to a putty-like gel solution that is then molded into the shape of the missing bone area. At this point, blood vessels begin to grow over the gel and the gel itself begins to dissolve. In its place, new bone begins to grow to close the gap.
This procedure, however, does not come cheap and is not covered by Medicaid. This issue is one that Dr. Clokie remains passionate about changing. Originally harvested from the bones of cadavers, he turned to Dr. Clokie later turned to a U.S. biotech firm in hopes of finding a new source. This firm was able to produce the protein in hamsters.
The next project is to start inserting the human gene that grows the needed protein into goat embryos, allowing the protein to be harvested directly from the milk they would produce. This would allow the cost to go down as well as the source to be able to keep producing it for a longer term.
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